Khusboo plays the owner of the garage in Bangalore, who falls in love with Prabhu's character, in her debut film, Dharmathin Thalaivan. She got instantly noticed for her charisma and acting skills.
Khusboo landed an intense role - a young woman who unsuccessfully fights for the love of her life, getting killed by her own cousin - in Fazil's Varusham Padhinaaru.In Kizhakku Vaasal, Khusboo plays the chirpy Selvi - a rich, spoilt girl, who unwittingly causes the death of the mother of the folk singer, who has a crush on her in Udhayakumar's Kizhakku VaasalKushboo is super-convincing as the girl-next-door, who is successfully wooed by a rich prince, who comes to the city to live a simple life like the underprivileged, in My dear Marthandan.Khusboo brings alive Nandhini - the home-schooled girl, who falls in love with a simpleton with a heart of gold, despite having her independence curbed by her overprotective brothers- in Chinna ThambiKhusboo is stunning as the kind-hearted Jennifer - the heir of a huge estate, who escapes the evil intentions of his father's big-brother, and claims what is rightfully hers, in Bramma.Khusboo's depiction of the college student, Subbu, who falls in love with a milk-man and stands with him for the rest of his life, took her to the next level. Her comedy scenes with Rajini are a riot.Amma Vanthaachu sees Khusboo as a bubbly, vibrant salesperson and a sober telephone operator. As a girlfriend, as a mother, Khushboo makes us invested in this emotional drama.Khusboo livens up the role of Sumathi, and along with Manoroma, who plays her guardian, makes sure the audience stay thoroughlu entertained, in Kamal Haasan's SingaravelanKhushbu became the gold standard in Tamil wives with KS Ravikumar's Purusha Latchanam. The moment she asked for Thaali varam, Khushoo was immortalised.Khusboo nails the character of a rich girl, who falls in love with a ordinary man from a lower class, marries him, and dies while giving birth to their daughter, in P Vasu'sKhusboo's depiction of the young wife, who gets caught in a perilous situation, while on vacation with his husband, in Bharathiraja's Captain Magal, got her many laurels.Kushboo is perfect as the ghazal singer, who visits a hill station to forget the murder of her mother, and meets a taxi driver, who brings a fresh perspective to her life, in Jaathi MalliKhusboo is one of the few female actors, who played the mother-in-law of the female lead, while at the peak of her career, and also aced it with oodles of charm in Nattamai. Kotta Paakkum went viral.In Sasi's Kolangal, Khusboo plays a survivor, who soldiers on, despite the brutal treatment from the men in her life, and further handles the harassment in the hands of her new in-lawsP Vasu's Pathithini saw Khushbu take on the role of a conflicted woman. It is unfortunate that the film didn't get its due. Khushbu won a special mention at the State Awards.Special mention 1: Khusboo is adorable as the wife of Keralite CBI officer, who comes to Chennai to investigate a case in Malabar Police. Her on-screen chemistry with Sathyaraj is just brilliant.Special mention 2: Khusboo matches steps with the inimitable Prabhu Dheva in the dance-anthem of the 90's, Metro Channel Munna Paaru (Indu).