We have earlier announced that Dhanush will be working next with Sekhar Kammula for his 51st film. The makers of the film have announced on Monday morning that Rashmika Mandanna will be joining the film. She will be paired opposite Dhanush for the first time. This is also the first time Rashmika will be working with director Sekhar Kammula. D51 is Dhanush's second straight Telugu film after the Venky Atluri directorial Sir.

D51 is produced by Narayan Das K Narang, Suneil Narang and Puskur Ram Mohan Rao under the banner Asian Cinemas LLP, in association with Sekhar's home banner Amigos Creations Pvt Ltd. Sonali Narang is the presenter of the film. Asian Cinemas has also produced Love Story, Sekhar Kammula's previous film, which starred Sai Pallavi and Naga Chaitanya. It may be noted that speculations before the announcement of the project suggested that Sai Pallavi would be signed on as the female lead for D51. 

Rashmika will be seen next in Pushpa: The Rule, the highly anticipated sequel of the 2021 Sukumar directorial Pushpa: The Rise. She is also set to appear next Rainbow, a Tamil-Telugu bilingual, opposite Dev Mohan and in Sandeep Reddy Vanga's Animal, opposite Ranbir Kapoor. She has recently opted out of the yet-to-be titled Nithin starrer that will be directed by Venky Kudumula.