Jeanine Mason will feature alongside Blair Underwood and Sarah Silverman in the psychological thriller, titled Viral. City of Angels star Underwood will also direct and produce the film.
Mason, best known for starring in Roswell, New Mexico, will play the wife of Underwood's character. The movie follows Andrew (Underwood), who falls into paranoia after his wife (Mason) goes missing.
Andrew tries to escape a self-destructive cycle via Emilia (Silverman), a victims advocate and self-help blogger who is dealing with her own demons from the past.
The cast also includes Clint James, Brendan Burke, Samuel Garnett, Jo Twiss and Connor Paolo.
Written by Joe McClean of Resident Evil: Vendetta fame, the movie is set to start shooting in New York next month.